Acid Reflux Medications Linked To Increased Migraine Risk, Study Suggests

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GUWAHATI: A recent study published in the journal Neurology Clinical Practice suggests that acid reflux medications could increase the risk of migraines in individuals who already suffer from severe headaches. Dr. Sudhir Kumar, a neurologist at Indraprastha Apollo Hospitals, highlighted this finding, which indicates that certain medications commonly used to treat acid reflux could be linked to a higher risk of migraines.

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The study, conducted by researchers from the University of Maryland in the United States, examined the relationship between acid-reducing drugs and migraines. It found that people taking proton pump inhibitors (PPIs) like omeprazole and esomeprazole, as well as histamine H2 receptor antagonists (H2RAs) such as cimetidine and famotidine, were at a greater risk of developing migraines and other severe headaches compared to those not taking these medications.

According to the study, PPIs were associated with a 70% higher risk of migraines, while H2RAs were linked to a 40% higher risk. Dr. Sudhir Kumar mentioned that these associations could be influenced by the comorbidity between gastrointestinal (GI) conditions and migraine disease.

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Dr. Kumar further explained that other studies have suggested a link between migraines and certain GI conditions, such as Helicobacter pylori infection, irritable bowel syndrome, celiac disease, peptic ulcers, gastroparesis, and gastroesophageal reflux disease (GERD). He mentioned that new cases of migraine have been reported after starting PPI or H2RA therapy, suggesting the need for further research to establish a definitive cause-effect relationship.