Low-fat vegan diet beneficial for improving cardiometabolic health in type 1 diabetes patients: Study
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USA: In a groundbreaking endeavor, researchers have conducted a 12-week randomized clinical trial examining the effect of a dietary intervention on insulin requirements and glycemic control in individuals with type 1 diabetes (T1D). The study findings offer promising insights into novel approaches for managing this chronic condition.The researchers found that a low-fat vegan diet — high... USA: In a groundbreaking endeavor, researchers have conducted a 12-week randomized clinical trial examining the effect of a dietary intervention on insulin requirements and glycemic control in individuals with type 1 diabetes (T1D). The study findings offer promising insights into novel approaches for managing this chronic condition. The researchers found that a low-fat vegan diet — high in carbohydrates and fiber and moderate in protein — increases insulin sensitivity, reduces insulin requirement, and improves glycemic control in individuals with type 1 diabetes versus a conventional portion-controlled diet. "In the vegan group, total and LDL cholesterol and blood urea nitrogen to creatinine ratio decreased. A1C decreased in both groups," the researchers reported in Clinical Diabetes. Hana Kahleova, Physicians Committee for Responsible Medicine, Washington, DC, and colleagues aimed to compare the effects of a low-fat vegan diet (without carbohydrate or portion restriction) to those of a portion-controlled diet in people with T1D. This trial comes at a crucial juncture, considering the rising prevalence of T1D globally and the persistent challenges associated with its management. The effects of a low-fat vegan diet were compared with a conventional portion-controlled, carbohydrate-controlled diet in 58 patients with T1D (age, ≥ 18 years) who had been receiving stable insulin treatment for the past 3 months. Participants were randomly assigned to receive either the vegan diet (n = 29), comprising grains, vegetables, fruits, and legumes, or the portion-controlled diet (n = 29) that reduced daily energy intake by 500-1000 kcal/d in overweight participants while maintaining a stable carbohydrate intake. The study's primary clinical outcomes included glycemic control (A1c), insulin sensitivity, and insulin requirement (total daily dose of insulin). Other assessments included the blood urea nitrogen, body weight, blood lipid profile, and blood urea nitrogen-to-creatinine ratio. 18 participants in the vegan diet group and 17 in the portion-controlled group completed the study. The study led to the following findings: "This study provides substantial support for a low-fat vegan diet that is high in carbohydrates and fiber, low in fat, and moderate in protein" and suggests the potential therapeutic use of this diet in type 1 diabetes management, the researchers wrote. Reference: Hana Kahleova, Tatiana Znayenko-Miller, Karen Smith, Cyrus Khambatta, Robby Barbaro, Macy Sutton, Danielle N. Holtz, Mark Sklar, Desiree Pineda, Richard Holubkov, Neal D. Barnard; Effect of a Dietary Intervention on Insulin Requirements and Glycemic Control in Type 1 Diabetes: A 12-Week Randomized Clinical Trial. Clin Diabetes 2024; cd230086. https://doi.org/10.2337/cd23-0086 Source : Clinical Diabetes Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751 Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: editorial@medicaldialogues.in. Contact no. 011-43720751MSc. Biotechnology